The information on the respective active substances is based on the latest scientific knowledge. They include specific information on pharmacokinetics, dosage and adverse effects in pregnant women, breastfeeding women, newborns and breast-fed children. For this purpose, SAPP has written monographs on more than 40 active substances, whose content and statements are based on original references (publications) which are accessible via Pubmed and / or are presented as accessible guidelines by internationally recognized specialist companies and organizations. Textbooks in this context are only very cautiously mentioned, since original references are often not found. The monographs are updated at regular intervals.